C17orf80

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C17orf80 protein abundance is significantly associated with the RNA expression of many other genes, with 8,925 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C17orf80-associated genes across cancer lineages are UNK, CRISPLD2, and MSI2. Each is linked with C17orf80 in more than 4 cancer types. Because this analysis shows association rather than direction, both C17orf80-to-partner and partner-to-C17orf80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C17orf80 versus UNK in HNSC, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf80→partner) and Y-score (partner→C17orf80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCUNK →+0.650+0.476<.001<.00125
BRCACRISPLD2 →-0.934-0.365<.001<.00134
HNSCMSI2 →+0.850+0.538<.001<.00134
BRCAAMZ2 →+0.395+0.316<.001<.00134
HNSCSNHG20 →+0.609+0.436<.001.00334
BRCAPLS3 →-1.002-0.462<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,925 associations by consensus.

C17orf80 vs UNK — HNSC

Per-sample scatter of C17orf80 vs UNK in HNSC (Pearson r = 0.26).

Explore this scatter interactively →

Exploration