C17orf80

Across TCGA cell cohorts, C17orf80 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,528 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C17orf80-associated GO terms across cancer lineages are Heterochromatin formation, Heterochromatin organization, and Nucleocytoplasmic transport. Each is linked with C17orf80 in more than 17 cancer types. Because this analysis shows association rather than direction, both C17orf80-to-partner and partner-to-C17orf80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by C17orf80-low versus C17orf80-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf80→partner) and Y-score (partner→C17orf80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Heterochromatin formation →	+0.092	+0.921	<.001	<.001	3	18
SOFT_TISSUE	Heterochromatin organization →	+0.087	+0.766	<.001	<.001	3	18
SOFT_TISSUE	Nucleocytoplasmic transport →	+0.089	+0.824	<.001	<.001	3	17
SOFT_TISSUE	RNA export from nucleus →	+0.135	+0.848	<.001	<.001	3	17
SOFT_TISSUE	Positive regulation of DNA metabolic process →	+0.063	+0.677	<.001	.001	3	17
SOFT_TISSUE	Nuclear transport →	+0.089	+0.824	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,528 associations by consensus.

Heterochromatin formation by C17orf80 expression — SOFT_TISSUE

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