C17orf80

Across TCGA cell cohorts, C17orf80 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C17orf80-associated genes across cancer lineages are KRTAP19-8, C1orf141, and LYZL4. Each is linked with C17orf80 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf80-to-partner and partner-to-C17orf80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP19-8 grouped by C17orf80-low versus C17orf80-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf80→partner) and Y-score (partner→C17orf80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	KRTAP19-8 →	+0.205	+3.807	<.001	.009	3	2
SKIN	C1orf141 →	+0.027	+4.467	<.001	.004	3	2
BLOOD_Leukemia	LYZL4 →	+0.052	+4.567	.001	.001	3	2
OVARY	GUCA1C →	+0.648	+3.700	.009	.004	3	1
OVARY	KRT28 →	+0.035	+3.444	.001	.003	3	1
OVARY	USP17L13 →	+0.006	+3.807	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

KRTAP19-8 by C17orf80 expression — OVARY

Explore this box plot interactively →