C17orf77

Across TCGA patient cohorts, C17orf77 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,588 significant associations in total. LAML shows the largest number of these associations.

The most reproducible C17orf77-associated GO terms across cancer lineages are Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, Cellular response to starvation, and Positive regulation of apoptotic process involved in morphogenesis. Each is linked with C17orf77 in more than 6 cancer types. Because this analysis shows association rather than direction, both C17orf77-to-partner and partner-to-C17orf77 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum grouped by C17orf77-low versus C17orf77-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf77→partner) and Y-score (partner→C17orf77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.037	+0.156	<.001	.003	3	6
SCLC	Cellular response to starvation →	+0.060	+0.228	<.001	<.001	2	7
ESCA	Positive regulation of apoptotic process involved in morphogenesis →	+0.079	+0.588	<.001	.003	3	6
LAML	Response to epidermal growth factor →	+0.039	+0.225	<.001	<.001	3	5
SCLC	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway →	+0.091	+0.176	.004	.001	3	5
SCLC	Negative regulation of gene expression, epigenetic →	+0.073	+0.176	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,588 associations by consensus.

Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum by C17orf77 expression — UCEC

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