C17orf77

Across TCGA pan-cancer cohorts, C17orf77 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of C17orf77’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where C17orf77 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C17orf77 is over-expressed in tumor, although a few such as BRCA and LIHC show the opposite, repressed pattern.

COAD, BRCA, and READ are the cancer types where C17orf77 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C17orf77 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	All	+1.366	<.001	9	view →
BRCA	All	III,IV	−0.210	.043	2	view →
READ	All	All	+1.377	.038	1	view →
LIHC	Female	All	+0.011	.043	1	view →
LIHC	Male	All	−0.006	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 4 lineages.

C17orf77–COAD

Open the COAD breakdown →