C17orf75

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C17orf75 protein abundance is significantly associated with the RNA expression of many other genes, with 14,987 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C17orf75-associated genes across cancer lineages are BIN2, NCKAP1L, and ENTPD1. Each is linked with C17orf75 in more than 7 cancer types. Because this analysis shows association rather than direction, both C17orf75-to-partner and partner-to-C17orf75 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C17orf75 versus BIN2 in OV, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf75→partner) and Y-score (partner→C17orf75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVBIN2 →-0.921-0.442<.001<.00138
GBMNCKAP1L →-0.767-0.253.002<.00138
OVENTPD1 →-0.664-0.445<.001<.00138
LSCCGIMAP5 →-0.586-0.332<.001<.00138
BRCAGAS7 →-0.657-0.243<.001<.00138
OVRASSF2 →-0.882-0.409.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,987 associations by consensus.

C17orf75 vs BIN2 — OV

Per-sample scatter of C17orf75 vs BIN2 in OV (Pearson r = -0.51).

Explore this scatter interactively →

Exploration