C17orf75

Across TCGA cell cohorts, C17orf75 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,333 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C17orf75-associated GO terms across cancer lineages are Interstrand cross-link repair, DNA replication, and Regulation of microtubule-based process. Each is linked with C17orf75 in more than 14 cancer types. Because this analysis shows association rather than direction, both C17orf75-to-partner and partner-to-C17orf75 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interstrand cross-link repair grouped by C17orf75-low versus C17orf75-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf75→partner) and Y-score (partner→C17orf75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	+0.092	+0.867	.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.124	+0.891	<.001	.001	3	15
LUNG_SCLC	Regulation of microtubule-based process →	+0.067	+0.799	.001	<.001	2	15
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.135	+0.891	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation involved in DNA replication →	+0.169	+0.798	.002	.006	3	14
UPPER_AERODIGESTIVE_TRACT	Mismatch repair →	+0.106	+0.763	<.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,333 associations by consensus.

Interstrand cross-link repair by C17orf75 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →