C17orf50

Across TCGA patient cohorts, C17orf50 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf50-associated genes across cancer lineages are RN7SL140P, MIR4742, and MIR6129. Each is linked with C17orf50 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf50-to-partner and partner-to-C17orf50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL140P grouped by C17orf50-low versus C17orf50-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf50→partner) and Y-score (partner→C17orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL140P →	+0.199	+4.997	<.001	.003	3	1
UCEC	MIR4742 →	+0.850	+3.943	.003	.007	3	1
UCEC	MIR6129 →	+0.795	+4.496	<.001	.002	3	1
UCEC	MIR6857 →	+0.611	+4.943	<.001	<.001	3	1
UCEC	RNU6-1205P →	+0.506	+3.690	.001	.009	3	1
UCEC	RNU6-899P →	+0.500	+3.871	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

RN7SL140P by C17orf50 expression — UCEC

Explore this box plot interactively →