C17orf49

Across TCGA patient cohorts, C17orf49 protein abundance is significantly associated with the RNA expression of many other genes, with 5,677 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C17orf49-associated genes across cancer lineages are SUGP1, NUP88, and SMC4. Each is linked with C17orf49 in more than 3 cancer types. Because this analysis shows association rather than direction, both C17orf49-to-partner and partner-to-C17orf49 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C17orf49 versus SUGP1 in LSCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf49→partner) and Y-score (partner→C17orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SUGP1 →	+0.405	+0.324	.004	.003	3	4
GBM	NUP88 →	+0.496	+0.528	<.001	<.001	3	3
LSCC	SMC4 →	+0.841	+0.333	<.001	.004	3	3
LSCC	DARS2 →	+0.730	+0.404	.002	.005	3	3
GBM	CENPF →	+1.152	+0.420	.001	<.001	3	3
LSCC	TMPO →	+0.782	+0.449	.005	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,677 associations by consensus.

C17orf49 vs SUGP1 — LSCC

Explore this scatter interactively →