C16orf95

Across TCGA patient cohorts, C16orf95 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf95-associated genes across cancer lineages are 14-3-3_beta, MEK1, and JNK2. Each is linked with C16orf95 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf95-to-partner and partner-to-C16orf95 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by C16orf95-low versus C16orf95-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf95→partner) and Y-score (partner→C16orf95) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.127	-2.986	.028	.037	2	1
UCEC	MEK1 →	+0.485	+3.000	.021	.037	2	1
UCEC	JNK2 →	+0.304	+3.000	.008	.037	1	1
UCEC	Caspase-7-cleavedD198 →	+0.923	+3.000	.007	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

14-3-3_beta by C16orf95 expression — UCEC

Explore this box plot interactively →