C16orf95

Across TCGA pan-cancer cohorts, C16orf95 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated C16orf95 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher C16orf95 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C16orf95 expression acts as an unfavorable survival marker, although some lineages such as LIHC and OV show a favorable association.

KIRC, ACC, and SKCM are the cancer types where C16orf95 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.794	0.944	<.001	93	view →
ACC	DFS	Median	All	0.512	0.929	<.001	53	view →
SKCM	OS	Median	All	0.738	0.824	.004	46	view →
LIHC	DFS	Median	III,IV	0.459	0.200	<.001	34	view →
OV	DFS	Median	IV	0.592	0.334	.001	24	view →
KIRP	DFS	Median	IV	0.039	0.594	.006	24	view →
MESO	DFS	Quartile	III,IV	0.286	0.505	.006	18	view →
SCLC	OS	Tertile	II,III,IV	0.861	0.610	.013	17	view →
UVM	OS	Quartile	III,IV	0.383	0.906	.012	17	view →
LGG	OS	Quartile	All	0.460	0.688	<.001	16	view →
SARC	DFS	Quartile	All	0.400	0.607	.007	13	view →
LUAD	DFS	Quartile	II,III,IV	0.505	0.677	.017	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

C16orf95–KIRC (OS)

Open the KIRC breakdown →