C16orf95

Across TCGA cell cohorts, C16orf95 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,360 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible C16orf95-associated GO terms across cancer lineages are Cellular senescence, Melanin biosynthetic process, and Melanin metabolic process. Each is linked with C16orf95 in more than 7 cancer types. Because this analysis shows association rather than direction, both C16orf95-to-partner and partner-to-C16orf95 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular senescence grouped by C16orf95-low versus C16orf95-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf95→partner) and Y-score (partner→C16orf95) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Cellular senescence →	+0.051	+0.612	.002	.001	3	8
LUNG_NSCLC_LUAD	Melanin biosynthetic process →	+0.966	+0.756	<.001	.002	3	7
LUNG_NSCLC_LUAD	Melanin metabolic process →	+0.966	+0.756	<.001	.002	3	7
BONE	Locomotory exploration behavior →	+0.187	+0.718	.002	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Basement membrane disassembly →	-1.059	-0.722	.003	.001	3	7
SOFT_TISSUE	Protein localization to microtubule plus-end →	+0.139	+0.531	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,360 associations by consensus.

Cellular senescence by C16orf95 expression — LARGE_INTESTINE

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