C16orf92

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C16orf92 mutation is significantly associated with the RNA expression of many other genes, with 212 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf92-associated genes across cancer lineages are RNA5SP391, RNA5SP517, and PTBP1. Each is linked with C16orf92 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf92-to-partner and partner-to-C16orf92 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP391 grouped by C16orf92-low versus C16orf92-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf92→partner) and Y-score (partner→C16orf92) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRNA5SP391 →+0.248+7.930<.001.00832
LUADRNA5SP517 →+0.448+7.930<.001.00832
SKCMPTBP1 →+0.388+3.214.009.00932
SKCMTAMM41 →+0.453+3.208.001.00932
SKCMUFD1 →+0.483+3.214.003.00932
SKCMSNORD115-20 →+0.217+4.219<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 212 associations by consensus.

RNA5SP391 by C16orf92 expression — LUAD

Box plot of RNA5SP391 in C16orf92-low vs C16orf92-high samples in LUAD.

Explore this box plot interactively →

Exploration