C16orf89

Across TCGA cell cohorts, C16orf89 mutation is significantly associated with the mutation status of many other genes, with 1,438 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible C16orf89-associated genes across cancer lineages are URI1, PHLPP1, and MYOM3. Each is linked with C16orf89 in more than 3 cancer types. Because this analysis shows association rather than direction, both C16orf89-to-partner and partner-to-C16orf89 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, URI1 grouped by C16orf89-low versus C16orf89-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf89→partner) and Y-score (partner→C16orf89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	URI1 →	+5.415	+5.415	.004	.004	1	4
OVARY	PHLPP1 →	+4.415	+4.977	.007	.007	1	3
OVARY	MYOM3 →	+5.415	+5.415	.004	.004	1	3
OVARY	CLSTN2 →	+4.415	+4.977	.007	.007	1	3
OVARY	PSIP1 →	+5.415	+5.415	.004	.004	1	3
OVARY	DMAP1 →	+5.415	+5.415	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,438 associations by consensus.

URI1 by C16orf89 expression — OVARY

Explore this box plot interactively →