C16orf87

Across TCGA patient cohorts, C16orf87 mutation is significantly associated with the RNA expression of many other genes, with 570 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf87-associated genes across cancer lineages are MIR1255B2, OR6K1P, and SH3BP1. Each is linked with C16orf87 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf87-to-partner and partner-to-C16orf87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1255B2 grouped by C16orf87-low versus C16orf87-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf87→partner) and Y-score (partner→C16orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR1255B2 →	+0.310	+3.461	.003	.003	3	2
BLCA	OR6K1P →	+0.052	+4.497	<.001	.009	3	2
UCEC	SH3BP1 →	+0.627	+2.595	.005	.006	3	1
UCEC	DMC1 →	+0.486	+3.754	.002	<.001	3	1
UCEC	TOMM22 →	+0.477	+3.354	.005	.005	3	1
UCEC	RTCB →	+0.526	+3.224	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 570 associations by consensus.

MIR1255B2 by C16orf87 expression — UCEC

Explore this box plot interactively →