C16orf87

Across TCGA pan-cancer cohorts, C16orf87 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated C16orf87 data layer compared with 3 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C16orf87 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C16orf87 expression acts as an unfavorable survival marker, although some lineages such as THYM and LGG show a favorable association.

HNSC, STAD, and KIRP are the cancer types where C16orf87 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.702	0.826	<.001	87	view →
STAD	DFS	Tertile	III,IV	0.402	0.746	<.001	52	view →
KIRP	DFS	Median	All	0.866	0.947	.001	51	view →
THCA	OS	Quartile	II,III,IV	0.577	1.000	.007	28	view →
LUAD	OS	Tertile	All	0.233	0.639	.006	25	view →
THYM	DFS	Median	All	0.867	0.651	.001	22	view →
LGG	OS	Quartile	All	0.847	0.633	<.001	21	view →
SARC	OS	Tertile	All	0.675	0.814	.010	21	view →
COAD	OS	Median	IV	0.847	0.244	.002	19	view →
KIRC	DFS	Tertile	IV	0.692	0.289	.016	14	view →
GBM	OS	Median	All	0.455	0.233	.010	12	view →
LUSC	DFS	Median	III,IV	0.546	0.865	.027	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

C16orf87–HNSC (OS)

Open the HNSC breakdown →