C16orf87

Across TCGA patient cohorts, C16orf87 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf87-associated genes across cancer lineages are HER3, PDCD4, and Bap1-c-4. Each is linked with C16orf87 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf87-to-partner and partner-to-C16orf87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HER3 grouped by C16orf87-low versus C16orf87-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf87→partner) and Y-score (partner→C16orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HER3 →	+0.487	+2.335	<.001	.020	3	1
UCEC	PDCD4 →	-0.728	-2.990	.002	.036	3	1
UCEC	Bap1-c-4 →	+0.229	+2.827	.037	.035	3	1
UCEC	Tuberin →	+0.373	+3.009	.005	.019	2	1
UCEC	Ku80 →	+0.302	+2.335	.010	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

HER3 by C16orf87 expression — UCEC

Explore this box plot interactively →