C16orf87

Across TCGA cell cohorts, C16orf87 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,336 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C16orf87-associated GO terms across cancer lineages are Chromosomal 5-methylcytosine DNA demethylation pathway, Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening, and DNA damage tolerance. Each is linked with C16orf87 in more than 11 cancer types. Because this analysis shows association rather than direction, both C16orf87-to-partner and partner-to-C16orf87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosomal 5-methylcytosine DNA demethylation pathway grouped by C16orf87-low versus C16orf87-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf87→partner) and Y-score (partner→C16orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.251	+0.999	.002	.003	3	12
LARGE_INTESTINE	Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.090	+0.928	<.001	<.001	3	12
BREAST	DNA damage tolerance →	+0.077	+0.893	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Nuclear pore organization →	+0.135	+0.750	<.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Transcription elongation-coupled chromatin remodeling →	+0.089	+0.754	.005	.004	3	11
LARGE_INTESTINE	Poly(A)+ mRNA export from nucleus →	+0.088	+0.625	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,336 associations by consensus.

Chromosomal 5-methylcytosine DNA demethylation pathway by C16orf87 expression — STOMACH

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