C16orf78

Across TCGA patient cohorts, C16orf78 mutation is significantly associated with the RNA expression of many other genes, with 1,230 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf78-associated genes across cancer lineages are RNA5SP71, CDADC1, and DHODH. Each is linked with C16orf78 in more than 2 cancer types. Because this analysis shows association rather than direction, both C16orf78-to-partner and partner-to-C16orf78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP71 grouped by C16orf78-low versus C16orf78-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf78→partner) and Y-score (partner→C16orf78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP71 →	+0.251	+5.177	.001	.007	3	3
SKCM	CDADC1 →	+0.417	+1.694	.004	.007	3	2
UCEC	DHODH →	+0.452	+2.332	<.001	.003	3	2
UCEC	RRP9 →	+0.407	+2.343	.008	.003	3	2
SKCM	MAP4 →	+0.490	+2.820	<.001	.001	3	2
LUAD	OR7E148P →	+0.053	+3.574	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,230 associations by consensus.

RNA5SP71 by C16orf78 expression — BLCA

Explore this box plot interactively →