C16orf70

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C16orf70 mutation is significantly associated with the RNA expression of many other genes, with 2,653 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf70-associated genes across cancer lineages are CORO1CP1, RNU6-822P, and RNU6-937P. Each is linked with C16orf70 in more than 2 cancer types. Because this analysis shows association rather than direction, both C16orf70-to-partner and partner-to-C16orf70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CORO1CP1 grouped by C16orf70-low versus C16orf70-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf70→partner) and Y-score (partner→C16orf70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCORO1CP1 →+0.235+5.516<.001.00433
SKCMRNU6-822P →+0.249+3.302<.001.00932
SKCMRNU6-937P →+0.309+3.018.003.00932
CESCNDUFS5P1 →+0.183+5.201<.001.00732
SKCMMTATP6P29 →+0.168+6.495<.001<.00132
LIHCPDCL3P1 →+0.066+5.544<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,653 associations by consensus.

CORO1CP1 by C16orf70 expression — COAD

Box plot of CORO1CP1 in C16orf70-low vs C16orf70-high samples in COAD.

Explore this box plot interactively →

Exploration