Across TCGA patient cohorts, C16orf54 mutation is significantly associated with the RNA expression of many other genes, with 169 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf54-associated genes across cancer lineages are MIR7702, ZNF479, and RN7SKP45. Each is linked with C16orf54 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf54-to-partner and partner-to-C16orf54 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf54→partner) and Y-score (partner→C16orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.338	+4.890	<.001	.002	3	2
SCLC	ZNF479 →	+0.121	+5.774	<.001	<.001	3	1
COAD	RN7SKP45 →	+0.175	+5.136	.004	.002	3	1
COAD	SNORD114-28 →	+0.365	+5.136	.003	.002	3	1
COAD	SNORD114-25 →	+0.672	+6.149	<.001	<.001	3	1
COAD	RNU6-1283P →	+0.639	+3.717	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 169 associations by consensus.

Exploration

C16orf54 survival (RNA) · tumor vs normal (RNA) · all C16orf54 data types