C15orf65

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, C15orf65 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C15orf65 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher C15orf65 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C15orf65 expression acts as an unfavorable survival marker.

BRCA are the cancer types where C15orf65 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCADFSMedianAll0.7450.949.0482view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

C15orf65–BRCA (DFS)

Kaplan–Meier survival curve for C15orf65 mutant vs wild-type samples in BRCA.

Open the BRCA breakdown →

Exploration