C15orf40

Across TCGA pan-cancer cohorts, C15orf40 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated C15orf40 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher C15orf40 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated C15orf40 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where C15orf40 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.858	0.573	.004	34	view →
PDAC	DFS	Median	II,III,IV	0.437	0.288	.010	14	view →
HNSC	OS	Quartile	IV	0.584	0.887	.014	12	view →
GBM	DFS	Quartile	All	0.212	0.496	.001	6	view →
LSCC	OS	Tertile	All	0.976	0.842	.022	5	view →
LUAD	OS	Median	III,IV	0.764	0.985	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

C15orf40–CCRCC (DFS)

Open the CCRCC breakdown →