C15orf40

Across TCGA patient cohorts, C15orf40 mutation is significantly associated with the RNA expression of many other genes, with 201 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C15orf40-associated genes across cancer lineages are RNA5SP502, RNU6-1292P, and L3MBTL2. Each is linked with C15orf40 in more than 1 cancer types. Because this analysis shows association rather than direction, both C15orf40-to-partner and partner-to-C15orf40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP502 grouped by C15orf40-low versus C15orf40-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C15orf40→partner) and Y-score (partner→C15orf40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP502 →	+0.417	+5.411	<.001	.005	3	2
UCEC	RNU6-1292P →	+0.330	+3.579	<.001	.002	3	2
UCEC	L3MBTL2 →	+0.374	+3.362	.009	.005	3	1
UCEC	USB1 →	+0.553	+2.617	<.001	.006	3	1
UCEC	VPS18 →	+0.636	+3.338	<.001	.005	3	1
UCEC	NFKBIB →	+0.585	+3.711	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 201 associations by consensus.

RNA5SP502 by C15orf40 expression — BLCA

Explore this box plot interactively →