C15orf40

Across TCGA cell cohorts, C15orf40 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,087 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C15orf40-associated GO terms across cancer lineages are Regulation of cell cycle checkpoint, Negative regulation of appetite by leptin-mediated signaling pathway, and Negative regulation of acute inflammatory response to antigenic stimulus. Each is linked with C15orf40 in more than 6 cancer types. Because this analysis shows association rather than direction, both C15orf40-to-partner and partner-to-C15orf40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell cycle checkpoint grouped by C15orf40-low versus C15orf40-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C15orf40→partner) and Y-score (partner→C15orf40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of cell cycle checkpoint →	+0.107	+0.963	.002	<.001	3	7
BREAST	Negative regulation of appetite by leptin-mediated signaling pathway →	+0.145	+0.759	<.001	.001	3	7
LUNG_NSCLC_LUAD	Negative regulation of acute inflammatory response to antigenic stimulus →	+0.096	+0.467	<.001	<.001	3	6
OESOPHAGUS	Circadian sleep/wake cycle →	+0.116	+0.829	.002	<.001	3	6
OESOPHAGUS	RNA import into nucleus →	+0.149	+0.794	.003	.003	3	6
URINARY_TRACT	Regulation of acute inflammatory response to antigenic stimulus →	+0.190	+0.833	.002	.006	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,087 associations by consensus.

Regulation of cell cycle checkpoint by C15orf40 expression — URINARY_TRACT

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