C14orf93

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C14orf93 mutation is significantly associated with the RNA expression of many other genes, with 1,809 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C14orf93-associated genes across cancer lineages are RNA5SP281, PPIAP5, and MIR6815. Each is linked with C14orf93 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf93-to-partner and partner-to-C14orf93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP281 grouped by C14orf93-low versus C14orf93-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf93→partner) and Y-score (partner→C14orf93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PRADRNA5SP281 →+0.788+7.939<.001.00831
LIHCPPIAP5 →+0.101+5.033.001.00931
SKCMMIR6815 →+0.409+5.797<.001.00131
UCECIGHV1-69D →+2.120+3.906<.001<.00131
UCECLINC01943 →+0.679+3.742<.001<.00131
UCECTRG-AS1 →+0.431+2.556<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,809 associations by consensus.

RNA5SP281 by C14orf93 expression — PRAD

Box plot of RNA5SP281 in C14orf93-low vs C14orf93-high samples in PRAD.

Explore this box plot interactively →

Exploration