C14orf93

Across TCGA cell cohorts, C14orf93 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C14orf93-associated genes across cancer lineages are CCDC182, GPX5, and DEUP1. Each is linked with C14orf93 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf93-to-partner and partner-to-C14orf93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC182 grouped by C14orf93-low versus C14orf93-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf93→partner) and Y-score (partner→C14orf93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CCDC182 →	+0.063	+4.700	.003	.002	3	1
OVARY	GPX5 →	+0.024	+4.228	<.001	.006	3	1
LARGE_INTESTINE	DEUP1 →	+0.400	+3.569	<.001	.006	3	1
LARGE_INTESTINE	OR2T8 →	+0.179	+3.584	<.001	.004	3	1
LARGE_INTESTINE	TMEM95 →	+0.014	+3.700	<.001	.009	3	1
BLOOD_Leukemia	NUDT10 →	+1.238	+3.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

CCDC182 by C14orf93 expression — OVARY

Explore this box plot interactively →