Across TCGA cell cohorts, C14orf180 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C14orf180-associated genes across cancer lineages are SSTR4, OR7G2, and OR13C7. Each is linked with C14orf180 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf180-to-partner and partner-to-C14orf180 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf180→partner) and Y-score (partner→C14orf180) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SSTR4 →	+0.061	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR7G2 →	+0.025	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR13C7 →	+0.023	+5.969	<.001	.001	3	1
BLOOD_Leukemia	ADAM7 →	+0.021	+4.922	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

C14orf180 survival (RNA) · tumor vs normal (RNA) · all C14orf180 data types