C14orf177

Across TCGA patient cohorts, C14orf177 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,608 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C14orf177-associated GO terms across cancer lineages are Negative regulation of supramolecular fiber organization, Protein polymerization, and Mitochondrial respiratory chain complex assembly. Each is linked with C14orf177 in more than 10 cancer types. Because this analysis shows association rather than direction, both C14orf177-to-partner and partner-to-C14orf177 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of supramolecular fiber organization grouped by C14orf177-low versus C14orf177-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf177→partner) and Y-score (partner→C14orf177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of supramolecular fiber organization →	+0.070	+0.101	<.001	<.001	3	11
STAD	Protein polymerization →	+0.081	+0.097	<.001	<.001	3	11
STAD	Mitochondrial respiratory chain complex assembly →	+0.102	+0.116	<.001	<.001	3	10
STAD	Negative regulation of post-translational protein modification →	+0.093	+0.108	<.001	<.001	3	10
STAD	Reactive oxygen species metabolic process →	+0.076	+0.102	<.001	<.001	3	10
STAD	Negative regulation of protein-containing complex assembly →	+0.079	+0.101	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,608 associations by consensus.

Negative regulation of supramolecular fiber organization by C14orf177 expression — STAD

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