C14orf177

Across TCGA pan-cancer cohorts, C14orf177 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated C14orf177 data layer compared with 4 for mutation status.

The strongest signal is observed in thyroid carcinoma (THCA), where higher C14orf177 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C14orf177 expression acts as an unfavorable survival marker, although some lineages such as SARC and KIRP show a favorable association.

THCA, KICH, and BLCA are the cancer types where C14orf177 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	II,III,IV	0.628	0.884	<.001	117	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	69	view →
BLCA	OS	Tertile	IV	0.150	0.600	<.001	54	view →
KIRC	DFS	Tertile	III,IV	0.212	0.516	.006	48	view →
SARC	OS	Tertile	All	0.908	0.684	.007	18	view →
TGCT	OS	Tertile	All	0.847	0.968	.028	18	view →
KIRP	DFS	Tertile	III,IV	0.762	0.315	.027	12	view →
STAD	OS	Quartile	IV	0.644	0.213	.023	9	view →
PCPG	DFS	Tertile	All	0.086	0.845	.013	9	view →
DLBC	OS	Tertile	III,IV	0.619	0.925	.048	6	view →
READ	OS	Tertile	III,IV	0.665	0.900	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

C14orf177–THCA (OS)

Open the THCA breakdown →