C14orf177

Across TCGA patient cohorts, C14orf177 mutation is significantly associated with the RNA expression of many other genes, with 90 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C14orf177-associated genes across cancer lineages are LINC00709, TUBB4BP5, and RNU6-34P. Each is linked with C14orf177 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf177-to-partner and partner-to-C14orf177 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00709 grouped by C14orf177-low versus C14orf177-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf177→partner) and Y-score (partner→C14orf177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC00709 →	+0.086	+8.930	<.001	<.001	3	2
COAD	TUBB4BP5 →	+0.386	+5.693	.001	.003	3	2
SKCM	RNU6-34P →	+0.144	+6.009	<.001	<.001	3	2
SKCM	SMSP1 →	+0.033	+2.931	<.001	.006	3	2
BRCA	RNU6-294P →	+0.219	+9.057	<.001	.003	3	1
BRCA	MTCYBP2 →	+0.139	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 90 associations by consensus.

LINC00709 by C14orf177 expression — LUAD

Explore this box plot interactively →