C14orf177

Across TCGA patient cohorts, C14orf177 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C14orf177-associated genes across cancer lineages are Neutrophils, CD4+ Tem, and CD8+ naive T-cells. Each is linked with C14orf177 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf177-to-partner and partner-to-C14orf177 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by C14orf177-low versus C14orf177-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf177→partner) and Y-score (partner→C14orf177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Neutrophils →	+0.019	+2.166	.001	.040	3	2
BRCA	CD4+ Tem →	+0.029	+6.234	<.001	.026	3	1
SKCM	CD8+ naive T-cells →	-0.035	-2.980	.041	.037	1	1
UCEC	Myocytes →	+0.040	+2.850	.042	.035	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Neutrophils by C14orf177 expression — UCEC

Explore this box plot interactively →