C14orf177

Across TCGA cell cohorts, C14orf177 RNA expression is significantly associated with the mutation status of many other genes, with 132 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C14orf177-associated genes across cancer lineages are SCLT1, MIDEAS, and ALG8. Each is linked with C14orf177 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf177-to-partner and partner-to-C14orf177 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCLT1 grouped by C14orf177-low versus C14orf177-high in SKIN.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf177→partner) and Y-score (partner→C14orf177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SCLT1 →	+4.437	+0.012	.004	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	MIDEAS →	+5.357	+0.026	.003	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	ALG8 →	+4.357	+0.020	.006	<.001	3	2
BLOOD_Myeloma	MSH6 →	+3.000	+0.597	.007	<.001	3	1
BLOOD_Myeloma	NCOR2 →	+3.321	+0.540	<.001	<.001	3	1
BLOOD_Myeloma	LRBA →	+4.000	+0.608	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 132 associations by consensus.

SCLT1 by C14orf177 expression — SKIN

Explore this box plot interactively →