C14orf119

Across TCGA pan-cancer cohorts, C14orf119 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated C14orf119 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher C14orf119 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated C14orf119 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, GBM, and LUAD are the cancer types where C14orf119 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	II,III,IV	1.000	0.512	.010	15	view →
GBM	DFS	Median	All	0.449	0.200	.002	12	view →
LUAD	DFS	Quartile	II,III,IV	0.330	0.691	.038	3	view →
LSCC	OS	Median	All	0.799	0.931	.025	2	view →
HNSC	DFS	Median	III,IV	1.000	0.937	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

C14orf119–CCRCC (DFS)

Open the CCRCC breakdown →