C14orf119

Across TCGA patient cohorts, C14orf119 mutation is significantly associated with the RNA expression of many other genes, with 2,785 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C14orf119-associated genes across cancer lineages are GAGE2E, RN7SL134P, and MIR6803. Each is linked with C14orf119 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf119-to-partner and partner-to-C14orf119 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE2E grouped by C14orf119-low versus C14orf119-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf119→partner) and Y-score (partner→C14orf119) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	GAGE2E →	+0.153	+6.149	<.001	.002	3	2
UCEC	RN7SL134P →	+0.129	+2.406	<.001	<.001	3	2
UCEC	MIR6803 →	+0.119	+4.086	<.001	.005	3	2
UCEC	CCL5 →	+1.038	+1.869	.001	.005	3	1
UCEC	POM121C →	+0.344	+1.901	.005	.004	3	1
UCEC	SYNRG →	+0.425	+2.280	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,785 associations by consensus.

GAGE2E by C14orf119 expression — LIHC

Explore this box plot interactively →