C14orf119

Across TCGA patient cohorts, C14orf119 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C14orf119-associated genes across cancer lineages are ATM, C-Raf, and eIF4E. Each is linked with C14orf119 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf119-to-partner and partner-to-C14orf119 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by C14orf119-low versus C14orf119-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf119→partner) and Y-score (partner→C14orf119) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.551	-2.571	.001	.010	3	2
UCEC	C-Raf →	+0.148	+2.584	.006	.010	3	2
UCEC	eIF4E →	+0.175	+3.183	.030	.009	3	1
UCEC	A-Raf_pS299 →	-0.178	-3.807	<.001	<.001	3	1
UCEC	ERK2 →	+0.185	+1.678	.012	.023	3	1
UCEC	JNK2 →	+0.298	+3.196	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

ATM by C14orf119 expression — UCEC

Explore this box plot interactively →