chromosome 13 open reading frame 42Genealiases: LINC00371 · LINC00372
Q-omics provides the consensus-scored C13orf42 profile across patient tissues and cancer cell-line models. C13orf42 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, C13orf42 is differentially expressed in 9, with the highest sampling consensus in KIRC. Additionally, C13orf42 RNA expression shows 6,887 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KICH, KIRC, and TGCT as cancer lineages where C13orf42 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for C13orf42 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes C13orf42 survival associations across molecular data types. C13orf42 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible C13orf42 RNA expression–survival associations across cancer types. High C13orf42 expression shows unfavorable associations in KICH, BRCA, DLBC, LUSC, UVM and READ. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for C13orf42 RNA expression.
This table summarizes C13orf42 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for C13orf42. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. C13orf42 shows lower tumor expression in KIRC, KIRP, LUAD, KICH, BRCA and LUSC. The KIRC box plot shows higher C13orf42 RNA expression in normal versus tumor tissue (log2 FC = −0.543, t-test p < 0.001).
This table shows molecular features associated with C13orf42 in patient tissues and cancer cell lines. In patient samples, C13orf42 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set. In cancer cell lines, C13orf42 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in PANCREAS, while CRISPR and shRNA rows add functional-dependency signals in BONE.
