Across TCGA patient cohorts, C12orf73 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C12orf73-associated genes across cancer lineages are MIR4727, MIR6782, and RFPL4AP6. Each is linked with C12orf73 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf73-to-partner and partner-to-C12orf73 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf73→partner) and Y-score (partner→C12orf73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4727 →	+0.758	+4.136	<.001	.001	3	1
UCEC	MIR6782 →	+0.633	+3.474	<.001	.006	3	1
UCEC	RFPL4AP6 →	+0.219	+3.676	<.001	.001	3	1
UCEC	RNU6-1318P →	+0.495	+3.943	<.001	.002	3	1
UCEC	DEFA7P →	+0.227	+4.132	<.001	.009	3	1
UCEC	RNU6-48P →	+0.664	+3.522	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

C12orf73 survival (RNA) · tumor vs normal (RNA) · all C12orf73 data types