Across TCGA pan-cancer cohorts, C12orf71 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C12orf71 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C12orf71 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C12orf71 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, THCA, and UCEC are the cancer types where C12orf71 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.223	0.677	.006	15	view →
THCA	DFS	Median	All	0.161	0.829	.007	9	view →
UCEC	DFS	Median	All	1.000	0.625	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: C12orf71 tumor-vs-normal RNA expression · all C12orf71 data types