C12orf57

Across TCGA patient cohorts, C12orf57 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,687 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible C12orf57-associated proteins across cancer lineages are PTMS, PTMS_S5, and HNRNPR. Each is linked with C12orf57 in more than 7 cancer types. Because this analysis shows association rather than direction, both C12orf57-to-partner and partner-to-C12orf57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf57 versus PTMS in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf57→partner) and Y-score (partner→C12orf57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PTMS →	+0.709	+0.886	.002	<.001	3	8
BRCA	PTMS_S5 →	+0.554	+0.800	<.001	<.001	3	5
GBM	HNRNPR →	+0.274	+0.269	.001	.004	3	5
GBM	TTC33 →	+0.359	+0.424	<.001	<.001	3	4
GBM	SART3 →	+0.253	+0.345	<.001	<.001	3	4
OV	TPI1 →	+0.399	+0.512	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,687 associations by consensus.

C12orf57 vs PTMS — OV

Explore this scatter interactively →