C12orf57

Across TCGA patient cohorts, C12orf57 protein abundance is significantly associated with the RNA expression of many other genes, with 18,410 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C12orf57-associated genes across cancer lineages are CYTIP, SLAMF6, and CD3D. Each is linked with C12orf57 in more than 4 cancer types. Because this analysis shows association rather than direction, both C12orf57-to-partner and partner-to-C12orf57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf57 versus CYTIP in HNSC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf57→partner) and Y-score (partner→C12orf57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CYTIP →	-1.361	-0.328	<.001	<.001	3	5
HNSC	SLAMF6 →	-1.165	-0.304	<.001	<.001	3	5
BRCA	CD3D →	-1.093	-0.285	.003	.006	3	5
LSCC	RHOH →	-0.827	-0.236	<.001	<.001	3	5
HNSC	CD79B →	-0.861	-0.254	<.001	<.001	3	5
HNSC	FGR →	-0.898	-0.259	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,410 associations by consensus.

C12orf57 vs CYTIP — HNSC

Explore this scatter interactively →