C12orf57

Across TCGA patient cohorts, C12orf57 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C12orf57-associated genes across cancer lineages are Neutrophils and Macrophages M2. Each is linked with C12orf57 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf57-to-partner and partner-to-C12orf57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by C12orf57-low versus C12orf57-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf57→partner) and Y-score (partner→C12orf57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	Neutrophils →	+0.007	+4.121	.002	.028	3	1
UCEC	Macrophages M2 →	-0.012	-2.881	.043	.038	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Neutrophils by C12orf57 expression — CESC

Explore this box plot interactively →