C12orf57

Across TCGA cell cohorts, C12orf57 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,299 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C12orf57-associated GO terms across cancer lineages are Psychomotor behavior, Motor behavior, and Regulation of Rho protein signal transduction. Each is linked with C12orf57 in more than 15 cancer types. Because this analysis shows association rather than direction, both C12orf57-to-partner and partner-to-C12orf57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Psychomotor behavior grouped by C12orf57-low versus C12orf57-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf57→partner) and Y-score (partner→C12orf57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Psychomotor behavior →	+0.301	+1.690	<.001	<.001	3	16
LARGE_INTESTINE	Motor behavior →	+0.127	+1.044	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of Rho protein signal transduction →	-0.091	-1.258	<.001	.001	3	10
STOMACH	Negative regulation of actin filament polymerization →	-0.118	-0.891	<.001	.001	2	10
LUNG_NSCLC_LUAD	Cell junction assembly →	-0.054	-1.033	<.001	<.001	3	9
LUNG_SCLC	COPII vesicle coating →	+0.086	+0.865	.003	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,299 associations by consensus.

Psychomotor behavior by C12orf57 expression — STOMACH

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