Across TCGA patient cohorts, C12orf56 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,591 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C12orf56-associated proteins across cancer lineages are CD74, DHX57, and DNMT3A. Each is linked with C12orf56 in more than 6 cancer types. Because this analysis shows association rather than direction, both C12orf56-to-partner and partner-to-C12orf56 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf56→partner) and Y-score (partner→C12orf56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD74 →	-0.628	-0.480	<.001	.003	2	7
LSCC	DHX57 →	+0.328	+1.245	<.001	<.001	3	5
OV	DNMT3A →	+0.670	+1.076	.001	.002	3	5
LUAD	TTK →	+0.692	+0.791	.007	.005	3	4
LSCC	XPO5 →	+0.584	+1.256	<.001	<.001	3	4
BRCA	NIP7 →	+0.441	+0.341	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,591 associations by consensus.

Exploration

C12orf56 survival (RNA) · tumor vs normal (RNA) · all C12orf56 data types