Across TCGA cell cohorts, C12orf56 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C12orf56-associated genes across cancer lineages are KIR2DS4, GP9, and OR5B3. Each is linked with C12orf56 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf56-to-partner and partner-to-C12orf56 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf56→partner) and Y-score (partner→C12orf56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	KIR2DS4 →	+0.013	+5.415	<.001	.004	3	2
BONE	GP9 →	+0.049	+5.169	<.001	.004	3	1
SKIN	OR5B3 →	+0.045	+5.415	<.001	.004	3	1
SKIN	KRTAP11-1 →	+0.022	+5.415	<.001	.004	3	1
SKIN	AADACL3 →	+0.006	+4.977	<.001	.007	3	1
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

C12orf56 survival (RNA) · tumor vs normal (RNA) · all C12orf56 data types