C12orf45

Across TCGA patient cohorts, C12orf45 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,946 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C12orf45-associated proteins across cancer lineages are C12orf45_S178, TMPO, and SIN3A. Each is linked with C12orf45 in more than 7 cancer types. Because this analysis shows association rather than direction, both C12orf45-to-partner and partner-to-C12orf45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf45 versus C12orf45_S178 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf45→partner) and Y-score (partner→C12orf45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C12orf45_S178 →	+0.868	+0.507	<.001	<.001	3	8
OV	TMPO →	+0.432	+0.422	.004	.001	3	7
BRCA	SIN3A →	+0.216	+0.216	.002	.006	3	7
HNSC	DHX9 →	+0.220	+0.473	<.001	.002	3	7
GBM	TCERG1 →	+0.258	+0.515	.001	.002	3	6
HNSC	PQBP1 →	+0.334	+0.483	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,946 associations by consensus.

C12orf45 vs C12orf45_S178 — LSCC

Explore this scatter interactively →