C12orf42

Across TCGA cell cohorts, C12orf42 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,713 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible C12orf42-associated GO terms across cancer lineages are Vacuolar transport, Establishment of protein localization to membrane, and Cellular response to molecule of fungal origin. Each is linked with C12orf42 in more than 6 cancer types. Because this analysis shows association rather than direction, both C12orf42-to-partner and partner-to-C12orf42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by C12orf42-low versus C12orf42-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf42→partner) and Y-score (partner→C12orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Vacuolar transport →	+0.047	+0.990	.002	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to membrane →	+0.036	+0.095	.001	.008	3	6
LUNG_SCLC	Cellular response to molecule of fungal origin →	+1.581	+0.806	<.001	<.001	3	5
LIVER	Extracellular matrix assembly →	-0.222	-0.145	.001	.009	3	5
BREAST	Cellular response to indole-3-methanol →	+0.135	+0.040	.005	.008	2	6
LUNG_SCLC	Response to molecule of fungal origin →	+1.581	+0.806	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,713 associations by consensus.

Vacuolar transport by C12orf42 expression — LUNG_SCLC

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