C12orf42

Across TCGA cell cohorts, C12orf42 mutation is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C12orf42-associated genes across cancer lineages are AVP, ZAN, and PGLYRP4. Each is linked with C12orf42 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf42-to-partner and partner-to-C12orf42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by C12orf42-low versus C12orf42-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf42→partner) and Y-score (partner→C12orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	AVP →	+0.097	+4.977	<.001	.002	3	1
SOFT_TISSUE	ZAN →	+0.004	+4.369	<.001	.008	3	1
SOFT_TISSUE	PGLYRP4 →	+0.012	+4.369	<.001	.008	3	1
SOFT_TISSUE	FTMT →	+0.065	+4.977	<.001	.002	3	1
URINARY_TRACT	OPRPN →	+0.045	+4.087	<.001	.009	3	1
URINARY_TRACT	OR2A2 →	+0.035	+4.087	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

AVP by C12orf42 expression — SOFT_TISSUE

Explore this box plot interactively →