C12orf4

Across TCGA patient cohorts, C12orf4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,218 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C12orf4-associated proteins across cancer lineages are STRAP, TIGAR, and PRRC2C. Each is linked with C12orf4 in more than 5 cancer types. Because this analysis shows association rather than direction, both C12orf4-to-partner and partner-to-C12orf4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf4 versus STRAP in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf4→partner) and Y-score (partner→C12orf4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	STRAP →	+0.256	+0.678	<.001	<.001	3	6
OV	TIGAR →	+0.403	+0.436	<.001	<.001	3	5
UCEC	PRRC2C →	+0.182	+0.357	.003	.004	3	5
COAD	CEP170 →	+0.304	+0.506	<.001	.001	3	5
OV	WNK1 →	+0.292	+0.570	<.001	<.001	3	5
COAD	MRPL1 →	-0.314	-0.368	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,218 associations by consensus.

C12orf4 vs STRAP — COAD

Explore this scatter interactively →