C12orf29

Across TCGA cell cohorts, C12orf29 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C12orf29-associated genes across cancer lineages are CST11, MYH4, and SCYGR1. Each is linked with C12orf29 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf29-to-partner and partner-to-C12orf29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST11 grouped by C12orf29-low versus C12orf29-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf29→partner) and Y-score (partner→C12orf29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CST11 →	+0.089	+4.887	.003	.009	3	1
LUNG_NSCLC_LUAD	MYH4 →	+0.013	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	SCYGR1 →	+0.189	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CST11 by C12orf29 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →